Then the book will be given to the one who is illiterate, saying, “Please read this.” And he will say, “I cannot read.”
Muslims claim that this prophecy was fulfilled when the angel Gabriel commanded Muhammad to recite the Qur'an:
Sahih al-Bukhari 3—The angel came to him and asked him to read. The Prophet replied, "I do not know how to read." The Prophet added, "Then the angel caught me (forcefully) and pressed me so hard that I could not bear it any more. He then released me and again asked me to read and I replied, 'I do not know how to read.'" ...
So does Isaiah 29:12 contain a prophesy about Muhammad? If so, then Muhammad stands condemned. For when we read the verse in context, we find that the entire passage is about judgment on people who are rebelling against God. I suggest reading all of Isaiah 29 to fully understand verse 12, but let's read vv. 9-14 to get the immediate context:
Be delayed and wait, blind yourselves and be blind; they become drunk, but not with wine, they stagger, but not with strong drink. For the Lord has poured over you a spirit of deep sleep, He has shut your eyes, the prophets; and He has covered your heads, the seers. The entire vision will be to you like the words of a sealed book, which when they give it to the one who is literate, saying, “Please read this,” he will say, “I cannot, for it is sealed.” Then the book will be given to the one who is illiterate, saying, “Please read this.” And he will say, “I cannot read.”
Then the Lord said, “Because this people draw near with their words and honor Me with their lip service, but they remove their hearts far from Me, and their reverence for Me consists of tradition learned by rote, therefore behold, I will once again deal marvelously with this people, wondrously marvelous; and the wisdom of their wise men will perish, and the discernment of their discerning men will be concealed.”
As we can see from the larger passage, Isaiah 29 is about God's judgment on a rebellious nation. People stubbornly refuse to obey God, so he curses them by taking away their discernment. Hence, if 29:12 is about Muhammad, then Muhammad couldn't have been a prophet. Instead, he was a stubborn rebel against God who used his illiteracy as an excuse to ignore God's revelations.
For more on Zakir Naik's claim that the Bible predicts the coming of Muhammad, see our longer video. For more on so-called Biblical prophecies about Muhammad, be sure to visit Answering Islam's page.